Ingredient Guide
Research-backed reference for skincare ingredients
Niacinamide
Also: Vitamin B3, Nicotinamide
Regulates oil production, minimizes pore appearance, evens skin tone, strengthens the skin barrier, reduces redness.
Among the most well-tolerated actives. Effective at 2–10%. Pairs well with hyaluronic acid, retinol, and zinc. Some users report mild warmth/flushing at higher concentrations.
Vitamin C (L-Ascorbic Acid)
Also: Ascorbic Acid
Potent antioxidant, brightens dark spots, boosts collagen, protects against UV damage.
Most bioavailable form but unstable (oxidizes with light/air). Can sting sensitive skin. Use in the morning under sunscreen. Derivatives (sodium ascorbyl phosphate, ascorbyl glucoside) are gentler alternatives.
Vitamin E
Also: Tocopherol, Tocopheryl Acetate
Antioxidant, moisturizes dry skin, soothes irritation, stabilizes vitamin C.
Well-tolerated and stable. Pairs synergistically with vitamin C and ferulic acid. Rare to irritate but a known allergen for some.
Panthenol
Also: Pro-Vitamin B5, Dexpanthenol
Humectant that hydrates, soothes irritation, and repairs the skin barrier.
Excellent for compromised or recovering skin. Very low irritation potential.
Alpha Arbutin
Also: Arbutin
Brightens dark spots by inhibiting tyrosinase, fades hyperpigmentation gently.
Gentle alternative to hydroquinone. Use at 2%. Pairs well with vitamin C and niacinamide. Always use sunscreen during the day.
Salicylic Acid (BHA)
Also: BHA
Oil-soluble exfoliant that penetrates pores, clears congestion, reduces blackheads and breakouts.
Start 2–3x weekly at 0.5–2%. Can dry the skin; follow with moisturizer. Avoid combining with other acids in the same routine. Not recommended during pregnancy.
Glycolic Acid (AHA)
Also: AHA
Smallest AHA molecule; exfoliates surface cells, smooths texture, evens tone, boosts glow.
Stronger and more irritating than other AHAs. Start weekly. Increases sun sensitivity — always use SPF. Avoid for sensitive or reactive skin.
Lactic Acid (AHA)
Also: Lactic Acid
Mild AHA that gently exfoliates while hydrating; smooths texture and brightens dullness.
Gentler than glycolic; a good beginner AHA. Also acts as a humectant. Use sunscreen during the day.
Mandelic Acid (AHA)
Also: Mandelic Acid
Gentlest AHA; antibacterial, large molecule, ideal for sensitive and acne-prone skin.
Large molecule = slower penetration = less irritation. Suited to melanin-rich skin types prone to PIH. Use sunscreen during the day.
Azelaic Acid
Also: Azelaic Acid
Reduces inflammation, fades hyperpigmentation, fights acne, calms rosacea.
Excellent for reactive skin and post-inflammatory hyperpigmentation. Safe during pregnancy. Effective at 10–20%.
Benzoyl Peroxide
Also: BPO
Kills acne-causing bacteria, reduces inflammation, treats inflammatory acne.
Start at 2.5%. Can bleach towels and clothing. Drying — use with a non-comedogenic moisturizer. Avoid combining with retinoids (oxidizes them).
Retinol
Also: Vitamin A
Speeds cell turnover, smooths fine lines, fades dark spots, clears acne, boosts collagen.
Begin 1–2x weekly at night. Expect 'purging' and dryness. Use SPF during the day. Avoid with AHAs, BHAs, and benzoyl peroxide. Not safe in pregnancy.
Retinaldehyde
Also: Retinal
Faster-acting than retinol with less irritation; anti-aging and acne-busting.
One conversion step closer to retinoic acid than retinol, so it works faster. Still irritating for newcomers — start slow. Not safe in pregnancy.
Bakuchiol
Also: Botanical Retinol
Plant-derived retinol alternative; smooths texture, evens tone, gentler profile.
Less data than retinol but no irritation/UV sensitivity. Safe during pregnancy. Pairs with other actives easily.
Tretinoin
Also: Retinoic Acid, ATRA, All-Trans Retinoic Acid
Gold-standard prescription retinoid; powerfully smooths wrinkles, clears acne, fades hyperpigmentation, and rebuilds collagen.
Prescription-only. Start at the lowest strength 2–3 nights weekly to limit peeling and 'retinization'. Always use SPF. Not safe in pregnancy or breastfeeding. Avoid layering with AHAs, BHAs, or benzoyl peroxide.
Peptides
Also: Matrixyl, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4
Signaling peptides that tell skin to build more collagen and elastin; soften fine lines and firm over time.
Gentle and well-tolerated — a good retinol alternative for sensitive skin. Results build over 8–12 weeks. Pairs well with niacinamide, hyaluronic acid, and antioxidants.
Copper Peptides
Also: GHK-Cu, Copper Tripeptide-1
Copper-bound peptides that support collagen, elastin, and wound healing; improve firmness and tone.
Avoid layering with strong antioxidants (vitamin C) and acids, which can destabilize the copper complex. May irritate very sensitive skin — patch-test.
Argireline
Also: Acetyl Hexapeptide-8, Acetyl Hexapeptide-3
Relaxes the appearance of expression lines around the eyes and forehead; a topical 'botox-like' peptide.
Effects are cosmetic and temporary with continued use. Well-tolerated; often combined with hyaluronic acid and other peptides.
Collagen
Also: Hydrolyzed Collagen, Marine Collagen, Soluble Collagen
Humectant and film-forming protein that hydrates and smooths the skin's surface.
Collagen molecules are too large to penetrate and replace your own collagen — topical collagen mainly hydrates and smooths. Oral collagen supplements have modest supportive evidence.
Hyaluronic Acid
Also: Sodium Hyaluronate
Holds up to 1000x its weight in water; plumps, hydrates, smooths fine lines.
Apply to damp skin and lock with moisturizer. In very dry climates it can draw water from the skin if not sealed — always follow with cream.
Glycerin
Also: Glycerol
Humectant that attracts water to the skin, plumps, smooths, repairs barrier.
Foundational, well-tolerated humectant. Effective across all skin types. Rarely irritates.
Squalane
Also: Olive Squalane, Sugarcane Squalane
Lightweight emollient that mimics skin sebum without clogging pores; softens and seals in moisture.
Comedogenic rating 1 — generally non-clogging. Stable and gentle. plant-derived squalane from sugarcane is most sustainable.
Aloe Vera
Also: Aloe Barbadensis Leaf Juice
Soothes irritation, hydrates lightly, calms inflamed or sun-exposed skin.
Generally well-tolerated but as a plant extract can rarely cause contact allergy. Soothing after sun.
Ceramides
Also: Ceramide NP, Ceramide EOP, Ceramide AP
Lipids that seal the skin barrier, retain moisture, soothe irritation, repair compromised skin.
Essential for compromised or aging skin. Pairs perfectly with niacinamide, glycerin, and hyaluronic acid. Especially useful after acids/retinoids.
Allantoin
Also: Alantoin
Soothes, softens, accelerates barrier repair, mildly exfoliates.
Excellent for compromised skin. Gentle and rarely irritating.
Zinc Oxide
Also: ZnO
Physical (mineral) sunscreen filter, broad-spectrum UVA/UVB protection, soothing for irritated and acne-prone skin.
Less likely to irritate than chemical filters; a good choice for reactive skin and post-procedure. Can leave a white cast on darker skin — micronized/tinted formulations help.
Titanium Dioxide
Also: TiO2
Physical filter; broad-spectrum protection, very stable and non-irritating.
Often paired with zinc oxide. UV-stable, fragrance-free compatible with reactive skin. White cast possible.
Avobenzone
Also: BMDM
Chemical UVA filter; absorbs aging UVA rays.
Photounstable — needs stabilizers; can irritate sensitive skin. Sometimes paired with octocrylene. Choose mineral filters if reactive.
Octinoxate
Also: Octyl Methoxycinnamate
Chemical UVB filter for sun protection.
Known contact allergen for some; banned in some reef-protection zones (Hawaii, Palau). Mineral filters are gentler alternatives.
Centella Asiatica
Also: Cica, Madecassoside
Calms inflammation, soothes irritation, supports healing, strengthens barrier.
Excellent for compromised, reactive, or post-treatment skin. Pair with panthenol and ceramides for repair.
Green Tea Extract
Also: EGCG, Camellia Sinensis
Antioxidant with polyphenols; reduces inflammation, protects against UV stress, soothe acne.
Beneficial but can be astringent at high concentrations. Generally well-tolerated.
Snail Mucin
Also: Snail Secretion Filtrate
Hydrates, soothes, supports repair, mild anti-aging, fade post-acne marks.
Widespread, well-tolerated. Avoid if you have a known dust mite allergy (cross-reactivity reported).
Tea Tree Oil
Also: Melaleuca Alternifolia
Antibacterial, anti-inflammatory, spot-treats acne.
Essential oil — never apply neat. Dilute to 1–5%; can cause contact dermatitis. Skip if sensitive.
Shea Butter
Also: Butyrospermum Parkii Butter
Rich plant butter that softens, nourishes, and seals in moisture; excellent for dry and compromised skin.
Comedogenic rating around 2 — generally fine, but very oily or acne-prone skin may prefer a lighter cream. Naturally rich in fatty acids and vitamins A and E.
Petrolatum
Also: Vaseline, Mineral Jelly
The most effective occlusive; reduces water loss by up to 98%, protecting and healing a compromised barrier.
Highly purified, non-comedogenic, and one of the safest moisturizers — a dermatology staple for 'slugging' and post-procedure care. Fragrance-free.
Dimethicone
Also: Polydimethylsiloxane
Silicone that smooths texture, fills fine lines, and forms a breathable barrier that locks in moisture.
Inert, non-comedogenic, and rarely irritating. Provides the silky feel in most moisturizers and primers. Does not 'suffocate' the skin.
Cetearyl Alcohol
Also: Cetyl Alcohol, Stearyl Alcohol, Fatty Alcohols
Fatty alcohol used as a cream thickener and emollient; softens and stabilizes emulsions.
Not the same as drying 'alcohol denat' — fatty alcohols are waxy emollients that condition and protect. Only an issue for the rare individual allergic to them.
Mineral Oil
Also: Paraffinum Liquidum, White Oil
Occlusive oil that softens skin and slows water loss; a classic, affordable moisturizer base.
Cosmetic-grade mineral oil is highly purified and non-comedogenic; myths about it clogging pores come from industrial grades. Well-tolerated and fragrance-free.
Lanolin
Also: Wool Wax, Lanolin Alcohol
Waxy emollient from sheep's wool that intensely moisturizes and seals cracked, very dry skin.
Very effective but a known contact allergen for some — patch-test if sensitive. Often found in lip balms and heavy creams.
Estriol
Also: Topical Estrogen, Estriol Cream
Prescription estrogen used in compounded creams; emerging evidence for improving menopausal skin thinning, dryness, and elasticity.
Prescription-only and controversial — use under medical supervision. Not suitable in pregnancy, breastfeeding, or with a history of hormone-sensitive cancers. Never self-prescribe from unregulated sources.
Estradiol
Also: Topical Estradiol
Potent topical estrogen studied for skin thickness, collagen, and hydration in menopause.
Stronger than estriol; prescription-only with the same cautions. Systemic absorption is a consideration — medical supervision is essential.
Fragrance
Also: Parfum, Perfume
Adds scent to products.
The #1 cause of contact allergic dermatitis in cosmetics. Industry blends are unlisted (trade-secret). Best to skip for sensitive or reactive skin.
Essential Oils
Also: Lavender Oil, Peppermint Oil, Lemon Oil
Scent and purported botanical actives.
Phototoxic (citrus oils) and sensitizing — common irritants even for non-sensitive skin. Frequent cause of slow-onset contact allergy.
Alcohol Denat
Also: Denatured Alcohol, SD Alcohol 40
Helps actives penetrate, lightens product feel, quick-drying.
Strips the skin barrier — increasing dryness, irritation, and TEWL. Long-term use worsens barrier. Cetyl/cetearyl/stearyl alcohol are formData emollients (SAFE) and unrelated.
Sodium Lauryl Sulfate
Also: SLS
Strong foaming surfactant (cleansers).
Harsh detergent that strips the skin barrier and worsens dry conditions (eczema, rosacea). Sodium laureth sulfate (SLES) is milder but can still irritate.
Oxybenzone
Also: Benzophenone-3
Chemical sunscreen filter.
Endocrine-disruptor concerns and a known allergen. Banned in reef-protection zones. Mineral filters (zinc/TiO2) are safer alternatives.
Based on peer-reviewed dermatological research. Educational only — not medical advice. Always patch-test new products and consult a dermatologist for personalized guidance.